Printable Biology Crosswords

Unravel the complexities of life itself, from microscopic cells to sprawling ecosystems. Explore genetics, evolution, and the wonders of the natural world.

6 puzzles, click Print on any puzzle below

Biology

Easy · 7×7 · 8 words
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Across

  1. 3. Muscular organ that pumps blood through the body
  2. 5. Breathing organ situated within the rib cage
  3. 7. Molecule that carries genetic information
  4. 8. Green, flattened structure attached to a stem

Down

  1. 1. Tube forming part of the blood circulation system
  2. 2. Main upward stalk of a plant
  3. 4. Organism such as trees, shrubs, and herbs
  4. 6. Heredity unit transferred from a parent to offspring

Biology

Hard · 11×11 · 13 words
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Across

  1. 1. A crying shame for a collection of similar cells?
  2. 3. Botanical life that shares a name with a Roman goddess.
  3. 5. Someone who is entirely full of themselves.
  4. 8. The director of a microscopic prison.
  5. 10. The solitary beginning of a complex life.
  6. 11. A rocky romance between fungi and algae.
  7. 12. Life's entire blueprint, spelled out in four letters.

Down

  1. 2. The empty space where thoughts jump.
  2. 3. Wildlife collection that sounds like a young deer with an extra vowel.
  3. 4. It plays a vital role in your body's symphony.
  4. 6. One of the options on a genetic menu.
  5. 7. A class of life that sounds like a burden.
  6. 9. Plumbing system that defies gravity in trees.

Biology

Medium · 11×11 · 15 words
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Across

  1. 1. Photosynthetic pond dwellers
  2. 4. Biological spark plug that accelerates chemical reactions
  3. 7. Microscopic hijacker that invades living cells
  4. 8. Organism with an identical genetic blueprint
  5. 10. Essential nutrient constructed from amino acid chains
  6. 13. The initial single-cell result of fertilization
  7. 14. Single-celled fungus responsible for making dough rise

Down

  1. 2. Organic compound category that includes fats and waxes
  2. 3. Hereditary unit that might be dominant or recessive
  3. 5. Organelle that acts as the cell's command center
  4. 6. How water naturally balances itself across a barrier
  5. 9. Scientific field focused on vegetation
  6. 10. Pale yellow fluid component of whole blood
  7. 11. Specialized cell transmitting nerve impulses
  8. 12. Major ecological community like a tundra or rainforest

Biology

Easy · 11×11 · 17 words
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Across

  1. 2. An inherited characteristic or distinguishing quality.
  2. 4. A microscopic infective agent that replicates inside host cells.
  3. 5. A distinct body part with a specific vital function.
  4. 8. The muscular organ that pumps blood throughout the body.
  5. 11. A green organism that uses photosynthesis to make food.
  6. 12. A flowering plant's unit of reproduction.
  7. 14. The control center of the central nervous system.

Down

  1. 1. A fiber that transmits sensation impulses to the brain.
  2. 2. A group of similar cells working together to perform a function.
  3. 3. A unit of heredity transferred from parent to offspring.
  4. 4. A tube carrying oxygen-depleted blood toward the heart.
  5. 6. The underground part of a plant that absorbs water.
  6. 7. A piece of hard, whitish tissue making up the skeleton.
  7. 9. A muscular tube carrying oxygenated blood away from the heart.
  8. 10. The red liquid that circulates in arteries and veins.
  9. 12. The natural outer covering of a human or animal body.
  10. 13. The molecule that carries genetic information.

Biology

Medium · 11×11 · 13 words
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Across

  1. 1. Homo sapiens is one
  2. 6. Hijacker of host cells
  3. 7. Botanical life of a region
  4. 9. Genetic typo
  5. 11. Fat molecule
  6. 12. Fungal seed equivalent
  7. 13. Cellular protein factory

Down

  1. 2. Taxonomic rank above class and below kingdom
  2. 3. Prehistoric evidence set in stone
  3. 4. Heart, liver, or lungs
  4. 5. Muscle building block
  5. 8. Cellular splitting process
  6. 10. Dolly the sheep was a famous one

CRISPR & Gene Editing

Hard · 11×11 · 13 words
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Across

  1. 1. Immune system soldier recently edited by CRISPR to hunt down solid tumors.
  2. 3. Cowardly, or the single letter of DNA changed without breaking the whole strand.
  3. 6. Optimus leader, or the next-gen editing technique that performs a precise 'search and replace'.
  4. 7. Ran wildly without the start? It's the nucleic acid that guides the molecular scissors.
  5. 8. Drinking tube alongside a small fruit, turned white by 2026 CRISPR tweaks.
  6. 9. Organic movie? Actually, a stubborn bacterial layer UCSD's new CRISPR tool strips resistance from.
  7. 11. Variant of a gene that sounds like a chorus of slippery fish.
  8. 12. Radiant light, or the therapeutics company making precise single-letter DNA changes.

Down

  1. 2. Like a fire-breathing monster of myth, describes the synthetic RNA combining two natural parts.
  2. 4. Aussie city whose researchers found a way to activate genes without any DNA cuts in 2026.
  3. 5. Chemical tags atop DNA that researchers are now tweaking to turn fetal blood genes back on.
  4. 6. Mild spa treatment ruined? It's a circular DNA ring used for gene delivery.
  5. 10. Non-stick cooking spray, or the essential 3-letter sequence Cas9 needs to lock on.
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